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Creamy Cajun Chicken Penne Pasta

Slovey Editorial Team

By Slovey Editorial Team

Published Apr 7, 2026

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Creamy Cajun Chicken Penne Pasta

Creamy Cajun Chicken Penne Pasta is a bold and flavorful dish that combines tender chicken, perfectly cooked pasta, and a rich, spicy cream sauce.

The Cajun seasoning adds a smoky kick, while the Parmesan cheese creates a smooth and creamy texture.

This easy recipe is perfect for weeknight dinners and delivers restaurant-quality flavor at home.

Why You’ll Love This Recipe

  • Quick and easy: Ready in under 30 minutes.
  • Bold flavor: Cajun spices bring heat and depth.
  • Creamy texture: Rich sauce coats every bite.
  • Family favorite: Perfect for busy nights.

About the Ingredients

Penne Pasta

Holds the creamy sauce well and provides a satisfying bite.

Chicken Breast

Lean protein that absorbs Cajun seasoning beautifully.

Cajun Seasoning

Adds spice, smokiness, and bold flavor.

Heavy Cream

Creates a rich and velvety sauce.

Parmesan Cheese

Enhances the sauce with a nutty, salty finish.

Tips & Tricks

Cook Pasta Al Dente

Prevents it from becoming mushy when mixed with sauce.

Season Well

Adjust Cajun seasoning to your spice preference.

Use Fresh Cheese

Freshly grated Parmesan melts better into the sauce.

Pro Tips

  • Add vegetables like bell peppers or spinach.
  • Use shrimp instead of chicken for variation.
  • Finish with fresh parsley for color and freshness.

Step-by-Step Instructions

Cook the Pasta

Boil pasta until al dente, then drain.

Cook the Chicken

Sauté seasoned chicken until fully cooked.

Make the Sauce

Add garlic, cream, and Parmesan, stirring until smooth.

Combine

Toss pasta with sauce and chicken until coated.

Delicious Variations

Spicy Version

Add extra Cajun seasoning or chili flakes.

Seafood Twist

Swap chicken for shrimp or scallops.

Light Version

Use half-and-half instead of heavy cream.

How to Store Creamy Cajun Chicken Penne Pasta

Refrigerator

Store for up to 3 days in an airtight container.

Freezer

Freeze for up to 1 month.

Reheating

Reheat gently with a splash of cream or milk.

Make Ahead

Prepare sauce ahead and combine when ready.

Frequently Asked Questions

Can I use a different pasta?

Yes, any short pasta works well.

Is it very spicy?

You can adjust the Cajun seasoning to taste.

Can I make it dairy-free?

Use dairy-free cream and cheese alternatives.

Can I add vegetables?

Yes, bell peppers, mushrooms, or spinach are great additions.

What protein alternatives can I use?

Shrimp or sausage work perfectly.

Creamy Cajun Chicken Penne Pasta

Creamy Cajun Chicken Penne Pasta

Creamy Cajun Chicken Penne Pasta

10 min
Prep Time
20 min
Cook Time
4
Servings
610
Calories

Ingredients

Instructions

  1. 1 Cook penne pasta until al dente, then drain.
  2. 2 Heat oil and cook seasoned chicken until browned and cooked through.
  3. 3 Add garlic and cook briefly.
  4. 4 Pour in heavy cream and stir.
  5. 5 Add Parmesan cheese and mix until smooth.
  6. 6 Toss in cooked pasta and combine.
  7. 7 Season with salt and pepper.
  8. 8 Serve garnished with parsley.

Servings: 4

Cuisine: American

Course: Dinner

Nutrition (per serving): 35g protein · 45g total carbs

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