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Melt-In-Your-Mouth Chicken Breast is one of those dependable dinner recipes that earns a permanent spot in your weekly meal rotation. With tender baked chicken, a creamy Parmesan topping, and simple pantry seasonings, this dish delivers maximum flavor with minimal effort. It’s a classic oven-baked chicken breast recipe that home cooks across America rely on for busy weeknights and relaxed family dinners.
This recipe is especially popular because it solves a common problem: dry, bland chicken breasts. The creamy mayonnaise and cheese coating locks in moisture while creating a lightly golden, flavorful topping that keeps the chicken juicy from edge to edge. No complicated techniques, no frying, and no expensive ingredients required.
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Perfect for meal prep, family dinners, or casual entertaining, this melt-in-your-mouth chicken recipe pairs well with nearly any side dish and fits comfortably into a practical, budget-friendly lifestyle.
Why You’ll Love This Recipe
- Simple preparation using everyday kitchen ingredients
- Extremely juicy and tender baked chicken breasts
- Rich, savory flavor with a creamy Parmesan topping
- Family-friendly and kid-approved dinner option
- Budget-conscious recipe using affordable proteins
- Ideal for busy weeknights and meal planning
- Easy to customize with spices, herbs, or cheese swaps
Ingredients Breakdown
• Boneless, Skinless Chicken Breasts – A lean, versatile protein that bakes beautifully when properly coated. Choosing evenly sized breasts ensures consistent cooking and tender results.
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• Mayonnaise – The key to ultra-moist chicken. Mayo melts as it bakes, sealing in juices while adding richness. Full-fat mayonnaise provides the best texture, but lighter versions can be used.
• Grated Parmesan Cheese – Adds salty, savory depth and helps create a lightly crisp, golden topping. Finely grated Parmesan blends smoothly into the creamy mixture.
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• Garlic Powder – Provides savory garlic flavor without overpowering the dish. It distributes evenly through the coating for balanced taste.
• Onion Powder – Adds subtle sweetness and depth, complementing both the chicken and the creamy topping.
• Paprika – Brings mild warmth and color to the dish. Smoked paprika can be used for a deeper, slightly smoky flavor.
• Salt – Enhances all the flavors and balances the richness of the sauce. Adjust to taste depending on the saltiness of your cheese.
• Black Pepper – Adds gentle heat and contrast to the creamy topping.
• Dried Parsley – Optional garnish that adds color and a light herbal note without overpowering the dish.

Tips and Tricks for Best Results
- Pound thick chicken breasts slightly to ensure even cooking
- Use a meat thermometer to avoid overcooking
- Spread the topping evenly to fully cover the chicken surface
- Avoid baking uncovered too long, which can dry the chicken
- Let the chicken rest after baking to keep juices inside
- Line the baking dish with parchment for easy cleanup
Variations and Customizations
This recipe is highly adaptable and works well with simple ingredient swaps.
- Replace mayonnaise with Greek yogurt or sour cream for a lighter version
- Use shredded mozzarella, cheddar, or a cheese blend instead of Parmesan
- Add Italian seasoning or dried herbs for extra flavor
- Mix panko breadcrumbs with the topping for a crispy crust
- Add cayenne pepper or red pepper flakes for heat
- Turn it into a one-pan meal by adding vegetables around the chicken
Pairing Suggestions
Melt-In-Your-Mouth Chicken Breast pairs well with a wide variety of sides, making it easy to build a complete meal.
Side Dishes
- Mashed potatoes or roasted potatoes
- Steamed broccoli or green beans
- Rice pilaf or buttered noodles
- Simple garden salad
Beverages
- Sparkling water or iced tea
- White wine like Chardonnay or Sauvignon Blanc
- Lemon-infused water
Occasions
- Weeknight family dinners
- Meal prep for lunches
- Casual dinner guests
- Comfort food nights
Storage Instructions
- Store leftovers in an airtight container in the refrigerator for up to 3 days
- Reheat gently in the oven or microwave to avoid drying out
- Freeze cooked chicken for up to 2 months, tightly wrapped
- Thaw overnight in the refrigerator before reheating
Popular Questions
Why does mayonnaise keep chicken moist?
Mayonnaise contains oil and eggs, which coat the chicken and prevent moisture loss during baking.
Can I use chicken thighs instead?
Yes, boneless skinless chicken thighs work well and may require slightly less baking time.
Can this recipe be made ahead?
Yes, assemble the chicken and topping ahead of time, cover, and refrigerate for up to 24 hours before baking.
How do I know when the chicken is done?
The internal temperature should reach 165°F when measured with a meat thermometer.
Is this recipe good for meal prep?
Absolutely. It reheats well and pairs easily with different sides throughout the week.

Melt-In-Your-Mouth Chicken Breast
Ingredients
Equipment
Method
- Preheat the oven to 375°F (190°C) and lightly grease or line a baking dish.
- In a mixing bowl, combine the mayonnaise, Parmesan cheese, garlic powder, onion powder, paprika, salt, and black pepper.
- Stir the mixture until smooth and well blended.
- Arrange the chicken breasts evenly in the prepared baking dish.
- Spoon the creamy mixture over each chicken breast and spread evenly.
- Bake uncovered for 35–40 minutes, until the chicken is cooked through.
- Check that the internal temperature of the chicken reaches 165°F (74°C).
- Remove from the oven and let rest for 2–3 minutes before serving.
- Garnish with dried parsley if desired and serve warm.
Notes
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